Zofran® (ondansetron) is a powerful anti-nausea medication marketed by GlaxoSmithKline. It was approved in 1991 to treat nausea and vomiting in patients undergoing surgery and chemotherapy.

Although it is not approved for use by pregnant women, Zofran® is sometimes prescribed off-label to treat morning sickness during pregnancy, including a severe form called hyperemesis gravidarum. It may be prescribed as a tablet, liquid or as an orally disintegrating tablet (ODT).


Zofran® (ondansetron), the popular anti-nausea medication sometimes used during pregnancy, has recently been linked to an increased risk of birth defects, according to new research.

The drug’s warning label does not indicate a risk of birth defect on its warning label, despite it being prescribed to treat morning sickness in some pregnancies. The manufacturer of Zofran® is currently under fire, being accused of illegally marketing Zofran® for morning sickness by failing to warn consumers and the medical community about the risks of Zofran® use during pregnancy.

Recently a number of studies have raised concern that taking Zofran® while pregnant increases the risk of birth defects, especially when used during the first trimester. Unfortunately, this is often when morning sickness during pregnancy is at its worst, which means women are more likely to be prescribed Zofran® during this risky time period.

Due to the Zofran® pregnancy category B, Zofran® is often prescribed to treat morning sickness despite the fact that the safety of taking Zofran® while pregnant has not been well studied.


Potential Zofran® birth defects found in recent studies include:

  • Cleft lip and cleft palate (2.4-fold increased risk)
  • Heart defects (doubled risk)
  • Kidney defects
  • Musculoskeletal defects
  • Poor fetal growth
  • Fetal death


Start by contacting a Zofran® attorney right now. We are here to listen, assess, and may be able to make a claim for financial compensation related to your newborn’s birth defect and its connection to the drug, Zofran®. Call us toll free at 1-855-566-4648 or fill out our contact form for a free consultation today.

We put your needs first and there is absolutely nothing to lose by a simple phone conversation with an experienced case manager in Zofran® lawsuits. We could potentially make a claim for your medical bills or the high expenses of medical care related to your newborn’s birth defect.

We can help you plan your future and relieve some of the burden Zofran® may have caused. All you need to do is make the first call toll free to Longo Legal at  1-855-566-4648 or complete our contact form and submit your information. Our consultations are free of charge and completely confidential.

This website is not sponsored by or affiliated with GlaxoSmithKline in any way; the lawyers responsible for this website are not affiliated with GlaxoSmithKline. Zofran® is a registered trademark of GlaxoSmithKline and/or their affiliates.