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Home / Uncategorized / Antidepressants and pregnancy

Antidepressants and pregnancy

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A recent study reported that taking serotonin reuptake antidepressants (SSRIs) during the second half of a woman’s pregnancy could more than double the risk that babies develop persistent pulmonary hypertension of the newborn (PPHN). High blood pressure in the lungs (called persistent pulmonary hypertension or PPHN) of newborns is a rare. But, it is a very serious birth defect.

The new study from Stockholm examined about 1.6 million births and was published in the British Medical Journal (BMJ). The result indicated that infants born to women who use selective serotonin reuptake inhibitors (SSRIs) during pregnancy had a twice the risk of developing persistent pulmonary hypertension. SSRIs are widely prescribed for depression under the names Zoloft, Prozac, Celexa, Lexapro, and Paxil.

Another study supports a possible causation between antidepressant use during pregnancy and PPHN. On July 19, 2006, the US Food and Drug Administration (FDA) warned that SSRI antidepressants can cause lung problems in newborns whose mothers took the medication while pregnant. The FDA warning came after a study showed that infants born to mothers who took SSRIs subsequent to the 20th week of gestation were 6 times more likely to have PPHN than infants who were not exposed to antidepressants during the mother’s pregnancy. That study was published in the New England Journal of Medicine.

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